Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 4/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4747586 | 0.94 | NOS3 (0.40) | HTR1ADRD2DRD1HTR1BHTR2A | |
| SCHEMBL4746896 | 0.88 | PDGFRB (0.39) | KDRHTR1ADRD2DRD1HTR1B | |
| Ammonia Solution, Strong SCHEMBL4750926 | 0.87 | PDGFRB (0.38) | KDRHTR1ADRD2DRD1HTR1B | |
| SCHEMBL4786874 | 0.78 | DRD2 (0.52) | SMN1; SMN2KDM4ENPY1RNPY2RTIPARP | |
| SCHEMBL4747507 | 0.78 | HTR6 (0.40) | HTR1ADRD2HTR2A | |
| SCHEMBL4747580 | 0.78 | POLB (0.37) | HRH1 | |
| SCHEMBL4839911 | 0.77 | DRD2 (0.54) | HTR1ADRD2DRD1HTR1BHTR2A | |
| SCHEMBL873501 | 0.77 | DRD2 (0.54) | HTR1ADRD2DRD1HTR1BHTR2A | |
| SCHEMBL873500 | 0.77 | DRD2 (0.54) | HTR1ADRD2DRD1HTR1BHTR2A | |
| SCHEMBL14157832 | 0.77 | DRD2 (0.54) | HTR1ADRD2DRD1HTR1BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130319-A2 | NOVEL N-TETRAHYDRONAPHTALENE OR N-CHROMANE CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2008-10-30 | — | — | WO | disclosed |