Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | DRD3 | P35462 | 2/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4786938 | 0.89 | DRD2 (0.47) | DRD2DRD3ADRA1ACHRM2CHRM1 | |
| SCHEMBL4210081 | 0.79 | DRD2 (0.79) | DRD2DRD3ADRA1ACHRM2CHRM1 | |
| SCHEMBL8076233 | 0.79 | DRD2 (0.79) | DRD2DRD3ADRA1ACHRM2CHRM1 | |
| SCHEMBL266921 | 0.79 | DRD2 (0.79) | DRD2DRD3ADRA1ACHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL4208502 | 0.78 | DRD2 (0.77) | DRD2DRD3ADRA1ACHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL4213402 | 0.78 | DRD2 (0.77) | DRD2DRD3ADRA1ACHRM2CHRM1 | |
| Hydrochloric Acid SCHEMBL7028613 | 0.78 | DRD2 (0.77) | DRD2DRD3ADRA1ACHRM2CHRM1 | |
| SCHEMBL4750047 | 0.78 | SMN1; SMN2 (0.39) | DRD2DRD1KDM4ENPY1RNPY2R | |
| SCHEMBL7023748 | 0.76 | DRD2 (0.46) | DRD2DRD3ADRA1APLAU | |
| SCHEMBL7023743 | 0.76 | DRD2 (0.46) | DRD2DRD3ADRA1APLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008130319-A2 | NOVEL N-TETRAHYDRONAPHTALENE OR N-CHROMANE CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2008-10-30 | — | — | WO | claimed |
| WO-2008130319-A2 | NOVEL N-TETRAHYDRONAPHTALENE OR N-CHROMANE CARBOXAMIDE DERIVATIVES FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2008-10-30 | — | — | WO | disclosed |