Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | AGXT | P21549 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | TACR1 | P25103 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30959761 | 1.00 | TSHR (0.47) | TSHRALDH1A1TAAR1LTA4HIDO1 | |
| SCHEMBL13279978 | 0.79 | ALDH1A1 (0.50) | TSHRALDH1A1TAAR1LTA4HNAAA | |
| SCHEMBL3369328 | 0.79 | MAOA (0.52) | TSHRALDH1A1TAAR1LTA4HIDO1 | |
| SCHEMBL26688770 | 0.77 | TSHR (0.48) | TSHRALDH1A1TAAR1LTA4HIDO1 | |
| SCHEMBL23857056 | 0.77 | TSHR (0.44) | TSHRALDH1A1TAAR1LTA4HNAAA | |
| SCHEMBL7689385 | 0.76 | ALDH1A1 (0.47) | TSHRALDH1A1TAAR1LTA4HNAAA | |
| SCHEMBL712647 | 0.75 | ALDH1A1 (0.49) | TSHRALDH1A1TAAR1LTA4HNAAA | |
| SCHEMBL1900502 | 0.74 | ALDH1A1 (0.46) | TSHRALDH1A1TAAR1LTA4HNAAA | |
| SCHEMBL1900505 | 0.74 | ALDH1A1 (0.46) | TSHRALDH1A1TAAR1LTA4HNAAA | |
| SCHEMBL11019198 | 0.73 | ALDH1A1 (0.44) | TSHRALDH1A1TAAR1LTA4HNAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008128064-A2 | TRUNCATED ANALOGS OF PEPTIDE AND POLYPEPTIDE THERAPEUTICS | TRUSTEES OF TUFTS COLLEGE (US) | 2008-10-23 | — | — | WO | disclosed |
| WO-2008116053-A2 | FAP-ACTIVATED CHEMOTHERAPEUTIC COMPOUNDS, AND METHODS OF USE THEREOF | TRUSTEES OF TUFTS COLLEGE (US) | 2008-09-25 | — | — | WO | disclosed |