Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750996 | 0.86 | ALDH1A1 (0.45) | POLBCYP2C19MAPTLMNAALDH1A1 | |
| SCHEMBL4751021 | 0.85 | SMN1; SMN2 (0.38) | POLBCYP2C19PPARGMAPTLMNA | |
| SCHEMBL4753294 | 0.81 | CYP2C19 (0.43) | POLBCYP2C19PPARGMAPTLMNA | |
| SCHEMBL4753147 | 0.79 | ALDH1A1 (0.45) | POLBPPARGMAPTLMNAALDH1A1 | |
| SCHEMBL4750797 | 0.78 | GRM5 (0.41) | POLBCYP2C19PPARGMAPTALDH1A1 | |
| SCHEMBL4751002 | 0.78 | ALDH1A1 (0.47) | ALDH1A1KMT2ATSHRL3MBTL1KDM4E | |
| SCHEMBL4751028 | 0.76 | ALDH1A1 (0.45) | POLBMAPTALDH1A1KMT2ATSHR | |
| SCHEMBL4753292 | 0.76 | CYP2C19 (0.41) | POLBCYP2C19PPARGTHRBMAPT | |
| SCHEMBL4751026 | 0.76 | MAPT (0.41) | POLBCYP2C19MAPTALDH1A1MEN1 | |
| SCHEMBL4750772 | 0.75 | ALDH1A1 (0.45) | POLBPPARGMAPTLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008147864-A2 | METHODS OF USING PIPERAZINE COMPOUNDS IN TREATING SODIUM CHANNEL-MEDIATED DISEASES OR CONDITIONS | XENON PHARMACEUTICALS INC. (CA) | 2008-12-04 | — | — | WO | disclosed |