Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MPI | P34949 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753147 | 0.90 | ALDH1A1 (0.45) | ALDH1A1KMT2AMAPTMPIHTT | |
| SCHEMBL4751026 | 0.86 | MAPT (0.41) | ALDH1A1KMT2AMAPTMPIHTT | |
| SCHEMBL4750792 | 0.86 | POLB (0.52) | ALDH1A1KMT2AMAPTMEN1NPC1 | |
| SCHEMBL4750772 | 0.85 | ALDH1A1 (0.45) | ALDH1A1KMT2AMAPTMPIHTT | |
| SCHEMBL4753349 | 0.85 | ALDH1A1 (0.47) | ALDH1A1KMT2AMAPTMPIHTT | |
| SCHEMBL4753111 | 0.84 | ALDH1A1 (0.42) | ALDH1A1KMT2AMAPTMPIHTT | |
| SCHEMBL4751002 | 0.84 | ALDH1A1 (0.47) | ALDH1A1KMT2AKDM4EL3MBTL1ALOX15 | |
| SCHEMBL4751028 | 0.82 | ALDH1A1 (0.45) | ALDH1A1KMT2AMAPTKDM4ETDP1 | |
| SCHEMBL4751013 | 0.81 | APP (0.40) | ALDH1A1KMT2AMAPTMPIHTT | |
| SCHEMBL4751015 | 0.81 | MAPT (0.43) | ALDH1A1KMT2AMAPTMPIHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008147864-A2 | METHODS OF USING PIPERAZINE COMPOUNDS IN TREATING SODIUM CHANNEL-MEDIATED DISEASES OR CONDITIONS | XENON PHARMACEUTICALS INC. (CA) | 2008-12-04 | — | — | WO | disclosed |