Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 2/20 | 0.69 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.69 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.69 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.69 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10669003 | 0.82 | PI4KA (1.00) | PI4KAPI4K2BPI4K2API4KBADORA3 | |
| SCHEMBL4751440 | 0.75 | CYP11B1 (0.47) | PI4KAPI4K2BPI4K2API4KBFDPS | |
| SCHEMBL21138183 | 0.75 | PI4KA (0.43) | PI4KAPI4K2BPI4K2API4KBSMN1; SMN2 | |
| SCHEMBL18232268 | 0.74 | PI4KA (0.44) | PI4KAPI4K2BPI4K2API4KBP2RX7 | |
| SCHEMBL4752076 | 0.73 | FDPS (0.43) | PI4KAPI4K2BPI4K2API4KBFDPS | |
| SCHEMBL10668441 | 0.71 | PI4KA (0.55) | PI4KAPI4K2BPI4K2API4KBHCAR1 | |
| SCHEMBL4752079 | 0.70 | PDE4A (0.39) | PI4KAPI4K2BPI4K2API4KBFDPS | |
| SCHEMBL21393153 | 0.66 | ADORA3 (0.37) | PI4KAPI4K2BPI4K2API4KBFDPS | |
| SCHEMBL24196376 | 0.66 | ADORA2A (0.65) | PI4KAPI4K2BPI4K2API4KBFGFR1 | |
| SCHEMBL19732711 | 0.66 | ADK (0.55) | PI4KAPI4K2BPI4K2API4KB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008131502-A2 | ANTIVIRAL COMPOUNDS OF THE ADAMANTANE TYPE | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2008-11-06 | — | — | WO | claimed |
| WO-2008131502-A2 | ANTIVIRAL COMPOUNDS OF THE ADAMANTANE TYPE | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2008-11-06 | — | — | WO | disclosed |