Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 8/20 | 0.48 |
| ▸ | HTR2A | P28223 | 8/20 | 0.48 |
| ▸ | DRD2 | P14416 | 5/20 | 0.48 |
| ▸ | DRD3 | P35462 | 4/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | DRD5 | P21918 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4789354 | 0.89 | HTR1A (0.39) | HTR1AHTR2ADRD2DRD3TMEM97 | |
| Hydrochloric Acid SCHEMBL4789017 | 0.89 | KCNH2 (0.49) | HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL4787404 | 0.86 | KCNH2 (0.51) | HTR1ADRD2SIGMAR1DRD4 | |
| Hydrochloric Acid SCHEMBL4789618 | 0.81 | FFAR4 (0.37) | HTR1ADRD2 | |
| Hydrochloric Acid SCHEMBL4907796 | 0.80 | GAA (0.56) | HTR1AHTR2ADRD2DRD3DRD1 | |
| SCHEMBL4750439 | 0.79 | SMN1; SMN2 (0.36) | DRD2DRD3KDM4EGAASLC6A2 | |
| SCHEMBL4788339 | 0.78 | KCNH2 (0.50) | HTR2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL4786832 | 0.77 | DRD2 (0.49) | HTR1ADRD2 | |
| SCHEMBL4750508 | 0.77 | FFAR4 (0.36) | HTR1AHTR2AALDH1A1MEN1LMNA | |
| SCHEMBL4789257 | 0.76 | SMN1; SMN2 (0.49) | HTR1AHTR2ASIGMAR1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | claimed |
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |