Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4788339 | 0.86 | KCNH2 (0.50) | KCNH2ABCB1SIGMAR1HTR2A | |
| Hydrochloric Acid SCHEMBL4789017 | 0.86 | KCNH2 (0.49) | KCNH2ABCB1SIGMAR1HTR2A | |
| SCHEMBL4751067 | 0.84 | HTR7 (0.47) | SMN1; SMN2ALDH1A1LMNAABCB1MEN1 | |
| Hydrochloric Acid SCHEMBL4787404 | 0.83 | KCNH2 (0.51) | KCNH2ABCB1SIGMAR1HTR1A | |
| SCHEMBL4751070 | 0.78 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL4750865 | 0.76 | HTR1A (0.48) | ALDH1A1LMNAMEN1KMT2ASIGMAR1 | |
| SCHEMBL4751068 | 0.75 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL4789354 | 0.75 | HTR1A (0.39) | ALDH1A1LMNAABCB1MEN1KMT2A | |
| SCHEMBL4751039 | 0.74 | ALDH1A1 (0.45) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL4750825 | 0.74 | ALDH1A1 (0.40) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146063-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT6 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR Nyilvánosan Müködö Részvénytársagág (HU) | 2008-12-04 | — | — | WO | disclosed |