Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | DRD4 | P21917 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4812505 | 0.81 | LMNA (0.41) | SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL4753181 | 0.79 | POLB (0.44) | ALDH1A1 | |
| SCHEMBL4750865 | 0.79 | HTR1A (0.48) | ALDH1A1LMNAMEN1KMT2AGAA | |
| SCHEMBL4750799 | 0.75 | POLB (0.42) | ALDH1A1 | |
| SCHEMBL4750480 | 0.75 | ALDH1A1 (0.39) | ALDH1A1LMNAMEN1KMT2AKDM4E | |
| SCHEMBL4752995 | 0.74 | GAA (0.51) | ALDH1A1MEN1KMT2AGAAKDM4E | |
| Hydrochloric Acid SCHEMBL4752998 | 0.72 | — | — | |
| SCHEMBL4750479 | 0.70 | MAPT (0.56) | SMN1; SMN2ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL4752471 | 0.69 | OPRM1 (0.42) | DRD2DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL4789354 | 0.69 | HTR1A (0.39) | ALDH1A1LMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | claimed |
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |