Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 5/20 | 0.45 |
| ▸ | PKM | P14618 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5491531 | 0.82 | HTR6 (0.41) | PKMALDH1A1POLBHTTMMP2 | |
| SCHEMBL14273105 | 0.76 | CA1 (0.62) | CA1CA2GAAPKMALDH1A1 | |
| SCHEMBL217862 | 0.70 | TP53 (0.69) | CA1CA2PKMALDH1A1HTT | |
| SCHEMBL1892163 | 0.70 | CA1 (0.59) | CA1CA2GAAPKMALDH1A1 | |
| SCHEMBL1364805 | 0.70 | CA1 (1.00) | CA1CA2GAAPKMALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28097128 | 0.69 | TP53 (0.67) | CA1CA2PKMALDH1A1HTT | |
| SCHEMBL6207072 | 0.69 | CA1 (0.53) | CA1CA2GAAPKMALDH1A1 | |
| SCHEMBL7257344 | 0.69 | PKM (0.46) | CA1CA2GAAPKMALDH1A1 | |
| SCHEMBL14431545 | 0.68 | GAA (0.62) | CA1CA2GAAPKMALDH1A1 | |
| SCHEMBL14973039 | 0.68 | GAA (0.54) | CA1CA2GAAPKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1937673-A1 | IMIDAZOLE DERIVATIVES AS INHIBITORS OF TAFIA | Sanofi-Aventis (FR) | 2008-07-02 | — | — | EP | disclosed |
| WO-2007045339-A1 | IMIDAZOLE DERIVATIVES AS INHIBITORS OF TAFIA | SANOFI-AVENTIS (DE) | 2007-04-26 | — | — | WO | disclosed |
| WO-2003013526-A1 | ANTICOAGULANT COMPOUNDS | MERCK & CO. INC. (US) | 2003-02-20 | — | — | WO | disclosed |
| US-5607948-A | PLATELET AGGREGATION INHIBITORS, BONE RESORPTION INHIBITORS | SUMITOMO PHARMACEUTICALS CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| EP-0706999-A1 | NOVEL DIPIPERIDINE DERIVATIVE | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1996-04-17 | — | — | EP | disclosed |