Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | PARL | Q9H300 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751273 | 0.82 | CA1 (0.53) | PKMCXCL8NOD1MMP2ALDH1A1 | |
| SCHEMBL752816 | 0.69 | CA1 (0.65) | HTR6PKMCYP2C9MMP2PARL | |
| SCHEMBL4728733 | 0.68 | TP53 (0.63) | HTR6PKMCYP2C9CYP3A4CYP2D6 | |
| SCHEMBL368482 | 0.68 | PKM (0.44) | HTR6PKMCYP2C9MMP2PARL | |
| SCHEMBL27989661 | 0.66 | GAA (0.71) | PKMPARLALDH1A1KMT2ALMNA | |
| SCHEMBL22112764 | 0.64 | PARL (0.48) | HTR6PKMCYP2C9MMP2PARL | |
| SCHEMBL28195638 | 0.64 | PKM (0.56) | HTR6PKMPARLALDH1A1POLB | |
| SCHEMBL16050475 | 0.64 | HTR6 (0.43) | HTR6PKMCXCL8NOD1CYP2C9 | |
| SCHEMBL14248621 | 0.63 | GAA (0.46) | HTR6PKMCXCL8NOD1PARL | |
| SCHEMBL7368521 | 0.63 | ALDH1A1 (0.40) | HTR6PKMCXCL8NOD1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740569-A1 | IMIDAZOLE DERIVATIVES USED AS TAFIA INHIBITORS | Sanofi-Aventis Deutschland GmbH (DE) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005105781-A1 | IMIDAZOLE DERIVATIVES USED AS TAFIA INHIBITORS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2005-11-10 | — | — | WO | disclosed |