Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | MC4R | P32245 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752864 | 1.00 | RAB9A (0.42) | RAB9AMC4REPHX2LMNATRPV1 | |
| SCHEMBL4751265 | 1.00 | RAB9A (0.42) | RAB9AMC4REPHX2LMNATRPV1 | |
| SCHEMBL4752862 | 1.00 | RAB9A (0.42) | RAB9AMC4REPHX2LMNATRPV1 | |
| SCHEMBL4751420 | 0.89 | RAB9A (0.35) | RAB9AMC4REPHX2TRPV1RBP4 | |
| SCHEMBL4752007 | 0.84 | MC4R (0.45) | MC4RLMNARBP4 | |
| SCHEMBL4871415 | 0.80 | MC4R (0.39) | MC4RRBP4TDP1 | |
| SCHEMBL4749130 | 0.80 | MC4R (0.44) | MC4RRBP4 | |
| SCHEMBL4749302 | 0.80 | MC4R (0.45) | MC4RLMNARBP4 | |
| SCHEMBL4751640 | 0.79 | MC4R (0.41) | MC4RRBP4TDP1 | |
| SCHEMBL4776650 | 0.79 | MC4R (0.44) | MC4RLMNARBP4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |