Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 6/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752021 | 1.00 | ALDH1A1 (0.38) | ALDH1A1MGLLCHRNA7CHRNB2CHRNB4 | |
| SCHEMBL4749213 | 0.88 | ALDH1A1 (0.32) | ALDH1A1MGLL | |
| SCHEMBL4749216 | 0.88 | ALDH1A1 (0.32) | ALDH1A1MGLL | |
| SCHEMBL4019273 | 0.83 | MGLL (0.35) | MGLL | |
| SCHEMBL4018836 | 0.83 | GRIN1 (0.38) | MGLL | |
| SCHEMBL4029076 | 0.83 | MGLL (0.35) | MGLL | |
| SCHEMBL4751751 | 0.82 | MGLL (0.39) | ALDH1A1MGLL | |
| SCHEMBL4749392 | 0.82 | MGLL (0.36) | MGLL | |
| SCHEMBL4751750 | 0.82 | MGLL (0.39) | ALDH1A1MGLL | |
| SCHEMBL4021646 | 0.82 | MC4R (0.36) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |