Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.36 |
| ▸ | MGLL | Q99685 | 6/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | MC3R | P41968 | 1/20 | 0.33 |
| ▸ | MC1R | Q01726 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 4/20 | 0.33 |
| ▸ | ESRRG | P62508 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4018836 | 0.89 | GRIN1 (0.38) | MGLLGRIN1GRIN2BKDM2BMEN1 | |
| SCHEMBL4025296 | 0.89 | MGLL (0.35) | MC4RMGLLNPC1RAB9AGRIN1 | |
| SCHEMBL4022812 | 0.89 | HTR6 (0.35) | MGLLKCNH2KDM2B | |
| SCHEMBL4752869 | 0.88 | MEN1 (0.40) | MGLLOPRM1MEN1KMT2A | |
| SCHEMBL4751351 | 0.88 | MEN1 (0.40) | MGLLOPRM1MEN1KMT2A | |
| SCHEMBL4749242 | 0.87 | OPRM1 (0.35) | MGLLNPC1RAB9AOPRM1MEN1 | |
| SCHEMBL4749224 | 0.87 | OPRM1 (0.35) | MGLLNPC1RAB9AOPRM1MEN1 | |
| SCHEMBL4020359 | 0.86 | MC4R (0.33) | MC4RMC3RMC1RKCNH2KDM2B | |
| SCHEMBL4749392 | 0.86 | MGLL (0.36) | MGLLGRIN1GRIN2BOPRM1KDM2B | |
| SCHEMBL4022170 | 0.85 | NPSR1 (0.42) | MGLLRAB9AGRIN1GRIN2BKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572814-B2 | 3,5-dibenzoyl-4-phenyl-piperidine anti-cancer compounds | CYTOKINETICS, INCORPORATED (US) | 2009-08-11 | — | — | US | claimed |
| EP-1962846-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-09-03 | — | — | EP | claimed |
| WO-2007059323-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-24 | — | — | WO | claimed |
| EP-1962846-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | Cytokinetics, Inc. (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007059323-A2 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2007-05-24 | — | — | WO | disclosed |