Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MC4R | P32245 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1490146 | 0.77 | LMNA (0.41) | KDM4EESR1ACHETAAR1ALDH1A1 | |
| SCHEMBL24620291 | 0.77 | KDM4E (0.40) | KDM4EESR1ACHETAAR1ALDH1A1 | |
| SCHEMBL22317583 | 0.76 | LMNA (0.43) | KDM4EESR1ACHEALDH1A1TP53 | |
| SCHEMBL8446375 | 0.76 | TAAR1 (0.41) | KDM4EESR1ACHETAAR1ALDH1A1 | |
| SCHEMBL31274920 | 0.74 | KDM4E (0.38) | KDM4EESR1ACHETAAR1ALDH1A1 | |
| SCHEMBL22067646 | 0.74 | ACHE (0.38) | ESR1ACHETAAR1ALDH1A1AOC3 | |
| SCHEMBL16316809 | 0.72 | LMNA (0.38) | KDM4EESR1ACHETAAR1ALDH1A1 | |
| SCHEMBL13153319 | 0.71 | KDM4E (0.36) | KDM4EESR1ACHETAAR1ALDH1A1 | |
| SCHEMBL5802807 | 0.71 | SIGMAR1 (0.51) | KDM4EALDH1A1LMNAMAPTL3MBTL1 | |
| SCHEMBL10620529 | 0.70 | ESR1 (0.47) | ESR1ACHETAAR1ALDH1A1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008138499-A1 | INSECTICIDAL SUBSTITUTED THIOUREA DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2008-11-20 | — | — | WO | disclosed |