Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751893 | 0.91 | MGLL (0.42) | ALDH1A1HPGDNPSR1L3MBTL1MGLL | |
| SCHEMBL4753498 | 0.89 | ALDH1A1 (0.48) | ALDH1A1POLBCYP2C19L3MBTL1MEN1 | |
| SCHEMBL4753413 | 0.86 | TDP1 (0.51) | POLBHPGDL3MBTL1MEN1KMT2A | |
| SCHEMBL4288263 | 0.83 | NPSR1 (0.43) | ALDH1A1POLBCYP2C19HPGDNPSR1 | |
| SCHEMBL4751878 | 0.80 | CYP1A2 (0.49) | ALDH1A1POLBCYP2C19HPGDL3MBTL1 | |
| SCHEMBL4752657 | 0.78 | SMN1; SMN2 (0.50) | ALDH1A1CYP2C19HPGDNPSR1MGLL | |
| SCHEMBL4296960 | 0.78 | L3MBTL1 (0.47) | ALDH1A1POLBCYP2C19L3MBTL1MGLL | |
| SCHEMBL4297012 | 0.77 | MEN1 (0.46) | ALDH1A1HPGDNPSR1MEN1KMT2A | |
| SCHEMBL4752576 | 0.77 | KMT2A (0.43) | ALDH1A1POLBCYP2C19MEN1KMT2A | |
| SCHEMBL4749712 | 0.76 | RAB9A (0.46) | ALDH1A1NPSR1L3MBTL1MGLLMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |