Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | SSTR2 | P30874 | 7/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.30 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4022834 | 0.84 | KDM2B (0.37) | CHRNB4CHRNA3SSTR2SSTR4SSTR3 | |
| SCHEMBL4021396 | 0.84 | BCHE (0.35) | — | |
| SCHEMBL4751400 | 0.83 | CFD (0.36) | CHRNB4CHRNA3SSTR2 | |
| SCHEMBL4020627 | 0.83 | KDR (0.33) | — | |
| SCHEMBL4023514 | 0.81 | CFD (0.36) | CHRNB4CHRNA3 | |
| SCHEMBL4774948 | 0.77 | KDM2B (0.35) | CHRNB4CHRNA3 | |
| SCHEMBL4749094 | 0.76 | KDM2B (0.34) | CHRNB4CHRNA3 | |
| SCHEMBL4749472 | 0.76 | MGLL (0.32) | CHRNB4CHRNA3 | |
| SCHEMBL4018815 | 0.75 | KDM2B (0.38) | KCNH2 | |
| SCHEMBL4029041 | 0.75 | KDM4E (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |