Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 9/20 | 0.32 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.30 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.30 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.30 |
| ▸ | REN | P00797 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751720 | 0.89 | ITGB3 (0.35) | MGLLREN | |
| SCHEMBL4749094 | 0.86 | KDM2B (0.34) | MGLLKDM2BCHRNB4CHRNA3 | |
| SCHEMBL4019114 | 0.86 | SIGMAR1 (0.38) | MGLLREN | |
| SCHEMBL4019124 | 0.86 | SIGMAR1 (0.38) | MGLLREN | |
| SCHEMBL4774948 | 0.84 | KDM2B (0.35) | MGLLKDM2BCHRNB4CHRNA3 | |
| SCHEMBL4751400 | 0.84 | CFD (0.36) | MGLLCHRNB4CHRNA3REN | |
| SCHEMBL4023514 | 0.83 | CFD (0.36) | MGLLCHRNB4CHRNA3REN | |
| SCHEMBL4022291 | 0.83 | MGLL (0.34) | MGLL | |
| SCHEMBL4022289 | 0.83 | MGLL (0.34) | MGLL | |
| SCHEMBL4020378 | 0.82 | MGLL (0.34) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | claimed |
| WO-2008140810-A1 | CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS | CYTOKINETICS, INCORPORATED (US) | 2008-11-20 | — | — | WO | disclosed |