Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 7/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18705001 | 0.73 | CHRM1 (0.72) | CHRM1HSD17B10KDM4EHRH3KCNH2 | |
| SCHEMBL25265146 | 0.72 | ALDH1A1 (0.46) | CHRM1HSD17B10KDM4EHRH3KCNH2 | |
| SCHEMBL4976767 | 0.72 | HSD17B10 (0.46) | CHRM1HSD17B10ALDH1A1LMNAKMT2A | |
| SCHEMBL25190840 | 0.72 | ALDH1A1 (0.46) | CHRM1HSD17B10KDM4EHRH3KCNH2 | |
| SCHEMBL28952927 | 0.72 | GPR119 (0.48) | CHRM1HSD17B10HRH3KCNH2 | |
| SCHEMBL27571753 | 0.71 | CYP2D6 (0.71) | CHRM1KDM4EALDH1A1KMT2A | |
| SCHEMBL1714913 | 0.69 | SLC6A2 (0.50) | KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL1514784 | 0.69 | MEN1 (0.46) | CHRM1KDM4EALDH1A1LMNAKMT2A | |
| SCHEMBL105769 | 0.68 | TRPA1 (0.57) | KCNH2TRPA1 | |
| SCHEMBL29611880 | 0.68 | KMT2A (0.69) | CHRM1KDM4EIDO1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008139941-A1 | SUBSTITUTED IMIDAZOLE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-11-20 | — | — | WO | disclosed |