Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753960 | 0.88 | MAPT (0.37) | LMNANPC1KDM4EFFAR4MCOLN3 | |
| SCHEMBL4750506 | 0.86 | AKT1 (0.36) | LMNANPC1KDM4EFFAR4MCOLN3 | |
| SCHEMBL4754001 | 0.82 | PKM (0.41) | LMNAKDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL4752959 | 0.77 | HTR2A (0.47) | LMNANPC1FFAR4ALDH1A1 | |
| SCHEMBL4750508 | 0.76 | FFAR4 (0.36) | LMNANPC1FFAR4ALDH1A1KMT2A | |
| SCHEMBL4788883 | 0.75 | TSHR (0.39) | LMNAALDH1A1GAATSHR | |
| SCHEMBL4751070 | 0.75 | ALDH1A1 (0.41) | LMNANPC1FFAR4ALDH1A1KMT2A | |
| SCHEMBL4789318 | 0.73 | AKT1 (0.34) | TSHR | |
| SCHEMBL7963661 | 0.71 | NPC1 (0.55) | LMNANPC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL4751068 | 0.70 | ALDH1A1 (0.41) | LMNANPC1KDM4EFFAR4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |