Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23402467 | 0.74 | BCHE (0.51) | ALDH1A1CNR2ALOX15GAAGRM1 | |
| SCHEMBL23402352 | 0.74 | BCHE (0.55) | ALDH1A1CNR2ALOX15GAAGRM1 | |
| SCHEMBL5426155 | 0.73 | NAPRT (0.71) | NAPRTALDH1A1MAPK1SMN1; SMN2ALOX15 | |
| SCHEMBL14023770 | 0.72 | ALDH1A1 (0.61) | ALDH1A1CNR2SMN1; SMN2ALOX15GAA | |
| SCHEMBL4318546 | 0.72 | ALDH1A1 (0.41) | NAPRTALDH1A1CYP3A4CYP2C9MAPK1 | |
| SCHEMBL23398632 | 0.72 | BCHE (0.56) | NAPRTALDH1A1ALOX15GAAGRM1 | |
| SCHEMBL23401070 | 0.72 | BCHE (0.53) | NAPRTALDH1A1ALOX15GAAGRM1 | |
| SCHEMBL4789171 | 0.70 | ALDH1A1 (0.41) | ALDH1A1CYP3A4CYP2C9MAPK1CYP2C19 | |
| SCHEMBL14023791 | 0.70 | KDM4E (0.44) | ALDH1A1CNR2MAPK1SMN1; SMN2ALOX15 | |
| Antipyrine SCHEMBL20452 | 0.70 | NAPRT (1.00) | NAPRTALDH1A1SMN1; SMN2ALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008141385-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2008-11-27 | — | — | WO | disclosed |
| WO-2008141385-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2008-11-27 | — | — | WO | disclosed |