Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4752960 | 0.70 | NAPRT (0.53) | ALDH1A1CYP3A4CYP2C9MAPK1CYP2C19 | |
| SCHEMBL7190295 | 0.69 | ALDH1A1 (0.42) | ALDH1A1CYP3A4CYP2C9MAPK1CYP2C19 | |
| Hydrochloric Acid SCHEMBL30612384 | 0.68 | ALDH1A1 (0.41) | ALDH1A1CYP3A4CYP2C9MAPK1CYP2C19 | |
| SCHEMBL15797759 | 0.67 | ALDH1A1 (0.40) | ALDH1A1CYP3A4CYP2C9MAPK1CYP2C19 | |
| SCHEMBL14023791 | 0.67 | KDM4E (0.44) | ALDH1A1MAPK1SMN1; SMN2NPSR1GAA | |
| SCHEMBL7782551 | 0.66 | NAPRT (0.42) | ALDH1A1MAPK1SMN1; SMN2GAAALOX15 | |
| SCHEMBL23402352 | 0.65 | BCHE (0.55) | ALDH1A1NPSR1GAAALOX15 | |
| SCHEMBL23402467 | 0.65 | BCHE (0.51) | ALDH1A1NPSR1GAAALOX15 | |
| SCHEMBL5265770 | 0.65 | NAPRT (0.50) | ALDH1A1SMN1; SMN2ALOX15 | |
| SCHEMBL9435157 | 0.65 | PGR (0.43) | ALDH1A1MAPK1SMN1; SMN2NPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008141385-A1 | VIRAL POLYMERASE INHIBITORS | BIOTA SCIENTIFIC MANAGEMENT PTY LTD (AU) | 2008-11-27 | — | — | WO | disclosed |