Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.58 |
| ▸ | DRD3 | P35462 | 7/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.58 |
| ▸ | HTR1A | P08908 | 5/20 | 0.58 |
| ▸ | HTR2A | P28223 | 4/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.53 |
| ▸ | HRH1 | P35367 | 3/20 | 0.53 |
| ▸ | HTR2B | P41595 | 3/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4787868 | 0.92 | DRD2 (0.50) | DRD2DRD3SLC6A4HTR1AHTR2A | |
| SCHEMBL4753185 | 0.83 | DRD2 (0.51) | DRD2DRD3SLC6A4HTR1AHTR2A | |
| SCHEMBL4788713 | 0.83 | OPRM1 (0.48) | DRD2DRD3SLC6A4HTR1AHTR2A | |
| SCHEMBL4750828 | 0.83 | HTR1A (0.51) | DRD2DRD3SLC6A4HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL4788380 | 0.82 | OPRM1 (0.58) | DRD2DRD3HTR1AHTR2AOPRM1 | |
| SCHEMBL4754022 | 0.80 | OPRM1 (0.49) | DRD2DRD3SLC6A4HTR1AHTR2A | |
| SCHEMBL4855972 | 0.79 | OPRL1 (0.65) | OPRM1OPRL1PLD1PLD2 | |
| SCHEMBL4786661 | 0.78 | KDM4E (0.40) | DRD2SLC6A4CYP1A2CYP2D6MEN1 | |
| SCHEMBL4752455 | 0.76 | OPRM1 (0.47) | DRD2DRD3SLC6A4HTR1AHTR2A | |
| Hydrochloric Acid SCHEMBL4817572 | 0.76 | OPRM1 (0.45) | DRD2DRD3SLC6A4HTR1AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |