Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 19/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.38 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.38 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750828 | 0.94 | HTR1A (0.51) | OPRM1HTR1AADRA2ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL4817572 | 0.88 | OPRM1 (0.45) | OPRM1HTR1AADRA2ADRD2HTR2A | |
| SCHEMBL4754005 | 0.81 | DRD2 (0.42) | OPRM1DRD2SLC6A4OPRL1OPRD1 | |
| SCHEMBL4754022 | 0.81 | OPRM1 (0.49) | OPRM1HTR1AADRA2ADRD2HTR2A | |
| SCHEMBL4752471 | 0.79 | OPRM1 (0.42) | OPRM1HTR1ADRD2HTR2ADRD3 | |
| SCHEMBL4750799 | 0.77 | POLB (0.42) | HTR2A | |
| SCHEMBL4753001 | 0.76 | DRD2 (0.58) | OPRM1HTR1AADRA2ADRD2HTR2A | |
| SCHEMBL4750861 | 0.76 | PLD2 (0.45) | OPRM1DRD2OPRL1 | |
| Water SCHEMBL4912684 | 0.74 | OPRL1 (0.52) | OPRM1DRD2OPRL1CHRM1 | |
| SCHEMBL4855972 | 0.73 | OPRL1 (0.65) | OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |