Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | PLD1 | Q13393 | 5/20 | 0.44 |
| ▸ | PLD2 | O14939 | 4/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750861 | 0.93 | PLD2 (0.45) | OPRM1DRD2PLD1PLD2HSD11B1 | |
| SCHEMBL4750828 | 0.87 | HTR1A (0.51) | OPRM1DRD2HTR1AADRA2AHTR2A | |
| SCHEMBL4752455 | 0.81 | OPRM1 (0.47) | OPRM1DRD2HTR1AADRA2AHTR2A | |
| SCHEMBL4753001 | 0.80 | DRD2 (0.58) | OPRM1DRD2HTR1AADRA2AHTR2A | |
| Hydrochloric Acid SCHEMBL4817572 | 0.80 | OPRM1 (0.45) | OPRM1DRD2HTR1AADRA2AHTR2A | |
| SCHEMBL4855972 | 0.74 | OPRL1 (0.65) | OPRM1PLD1PLD2 | |
| Hydrochloric Acid SCHEMBL4787868 | 0.73 | DRD2 (0.50) | OPRM1DRD2HTR1AADRA2AHTR2A | |
| SCHEMBL7709273 | 0.73 | OPRM1 (0.72) | OPRM1DRD2HTR1AADRA2AHTR2A | |
| SCHEMBL4752471 | 0.71 | OPRM1 (0.42) | OPRM1DRD2HTR1AHTR2ADRD3 | |
| SCHEMBL25802931 | 0.71 | OPRM1 (0.70) | OPRM1DRD2HTR1AADRA2AHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146064-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT7 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR (HU) | 2008-12-04 | — | — | WO | disclosed |