Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29763197 | 0.80 | KEAP1 (0.54) | MGLLHTR1AADRA1BHTR6KEAP1 | |
| SCHEMBL3975556 | 0.80 | KEAP1 (0.54) | MGLLHTR1AADRA1BHTR6KEAP1 | |
| SCHEMBL30263414 | 0.80 | KEAP1 (0.48) | MGLLHTR1AADRA1BHTR6KEAP1 | |
| SCHEMBL570340 | 0.80 | KEAP1 (0.48) | MGLLHTR1AADRA1BHTR6KEAP1 | |
| SCHEMBL3021427 | 0.78 | KEAP1 (0.57) | MGLLHTR1AADRA1BKEAP1MAPK1 | |
| SCHEMBL219341 | 0.77 | ADRB1 (0.59) | HTR1AADRA1BADRB1HTTALDH1A1 | |
| SCHEMBL1035343 | 0.75 | GAA (0.59) | MAPK1HTTGAAALDH1A1LMNA | |
| SCHEMBL9579357 | 0.75 | MGLL (0.39) | MGLLHTR1AHTR6KEAP1DNMT1 | |
| SCHEMBL1929031 | 0.75 | ADRA2C (0.60) | HTR1AADRA1BHTR6MAPK1LMNA | |
| SCHEMBL10677139 | 0.75 | HTR6 (0.62) | HTR1AHTR6ADRB1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146063-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT6 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR Nyilvánosan Müködö Részvénytársagág (HU) | 2008-12-04 | — | — | WO | disclosed |