Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13845045 | 0.79 | — | — | |
| SCHEMBL8602360 | 0.76 | KDM4E (0.42) | — | |
| SCHEMBL20780055 | 0.75 | SIGMAR1 (0.34) | HTR7 | |
| SCHEMBL30587815 | 0.72 | CES1 (0.31) | — | |
| SCHEMBL5083188 | 0.71 | DRD2 (0.47) | RAB9ATSHR | |
| SCHEMBL6809208 | 0.71 | KDM4E (0.44) | TSHR | |
| SCHEMBL13415331 | 0.70 | DRD2 (0.46) | RAB9ATSHR | |
| SCHEMBL22492285 | 0.69 | HTT (0.45) | RAB9ATSHR | |
| SCHEMBL13415965 | 0.69 | BRD4 (0.44) | TSHR | |
| SCHEMBL6407033 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022272060-A1 | EP2 ANTAGONIST COMPOUNDS | RESERVOIR NEUROSCIENCE, INC. (US) | 2022-12-29 | — | — | WO | disclosed |
| EP-2066648-B1 | SUBSTITUTED DIMETHYLCYCLOBUTYL COMPOUNDS, THEIR PREPARATION AND USE IN MEDICAMENTS | ESTEVE LABOR DR (ES) | 2017-04-12 | — | — | EP | disclosed |
| US-20100105680-A1 | SUBSTITUTED DIMETHYLCYCLOBUTYL COMPOUNDS, THEIR PREPARATION AND USE IN MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2010-04-29 | — | — | US | disclosed |
| WO-2008147246-A1 | CATALYST FOR DEHYDROGENATION OF 4,5,6,7 TETRAHYDROINDOLE INTO INDOLE AND METHOD FOR PREPARING THEREOF | A.E. FAVORSKY IRKUTSK INSTITUTE OF CHEMISTRY SIBERIAN BRANCH RUSSIAN ACADEMY OF SCIENCES (IRIH SB RAS) (RU) | 2008-12-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100105680-A1 | SUBSTITUTED DIMETHYLCYCLOBUTYL COMPOUNDS, THEIR PREPARATION AND USE IN MEDICAMENTS | SIGMAR1, TMEM97, OPRK1 | RAB9A 4530/4885TSHR 785/4885HTR7 185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.