Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 7/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7608 | 0.84 | CA1 (0.52) | ALDH1A1MEN1KMT2ACA1CA2 | |
| Pyridine SCHEMBL2802133 | 0.81 | ALDH1A1 (0.46) | ALDH1A1LMNASMN1; SMN2NR2F2HTT | |
| SCHEMBL4013923 | 0.76 | RAPGEF4 (0.63) | ALDH1A1HTTMEN1KMT2ACA1 | |
| 1-Methylimidazole SCHEMBL6445728 | 0.75 | LMNA (0.48) | ALDH1A1LMNASMN1; SMN2NR2F2HTT | |
| Pyridine SCHEMBL1596384 | 0.73 | ALDH1A1 (0.52) | ALDH1A1LMNASMN1; SMN2HTTKMT2A | |
| Toluene SCHEMBL27551962 | 0.72 | TSHR (0.48) | ALDH1A1LMNASMN1; SMN2HTTMEN1 | |
| Pyridine SCHEMBL2712566 | 0.72 | TSHR (0.56) | ALDH1A1LMNAMEN1KMT2ARECQL | |
| SCHEMBL23172333 | 0.71 | CA1 (0.44) | ALDH1A1MEN1KMT2ACA1CA2 | |
| Pyridine SCHEMBL7211274 | 0.70 | ALDH1A1 (0.47) | ALDH1A1LMNASMN1; SMN2HTTSLC40A1 | |
| Pyridine SCHEMBL873759 | 0.70 | TDP1 (0.53) | ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140973-A1 | SEMI-SYNTHETIC GLYCOPEPTIDES WITH ANTIBACTERIAL ACTIVITY | LEAD THERAPEUTICS, INC. (US) | 2008-11-20 | — | — | WO | disclosed |