Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA1 | Q09470 | 5/20 | 0.53 |
| ▸ | KCNAB1 | Q14722 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753834 | 0.95 | KCNA1 (0.51) | KCNA1KCNAB1ALDH1A1LMNAHPGD | |
| SCHEMBL13983989 | 0.90 | KCNA1 (0.66) | KCNA1KCNAB1ALDH1A1LMNAHPGD | |
| SCHEMBL4751184 | 0.84 | KDM4E (0.52) | KCNA1KCNAB1ALDH1A1LMNAKDM4E | |
| Ammonia Solution, Strong SCHEMBL4811566 | 0.83 | KDM4E (0.51) | KCNA1KCNAB1ALDH1A1LMNAKDM4E | |
| SCHEMBL4753862 | 0.82 | KCNA1 (0.65) | KCNA1KCNAB1ALDH1A1LMNAHPGD | |
| SCHEMBL4752355 | 0.81 | KCNA1 (0.49) | KCNA1KCNAB1ALDH1A1LMNAHPGD | |
| SCHEMBL13983859 | 0.80 | KCNA1 (0.52) | KCNA1KCNAB1ALDH1A1LMNAHPGD | |
| SCHEMBL13983881 | 0.74 | KCNA1 (0.61) | KCNA1KCNAB1ALDH1A1HPGDKDM4E | |
| SCHEMBL4753300 | 0.72 | ALDH1A1 (0.45) | ALDH1A1LMNAHPGDHTTKDM4E | |
| SCHEMBL4751511 | 0.71 | KCNA1 (0.72) | KCNA1KCNAB1ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008149163-A2 | POTASSIUM ION CHANNEL MODULATORS AND USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2008-12-11 | — | — | WO | claimed |
| WO-2008149163-A2 | POTASSIUM ION CHANNEL MODULATORS AND USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2008-12-11 | — | — | WO | disclosed |
| WO-2008149163-A2 | POTASSIUM ION CHANNEL MODULATORS AND USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2008-12-11 | — | — | WO | disclosed |