Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | CD4 | P01730 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4751184 | 0.87 | KDM4E (0.52) | ALDH1A1GAACD4SMN1; SMN2KDM4E | |
| Ammonia Solution, Strong SCHEMBL4811566 | 0.86 | KDM4E (0.51) | ALDH1A1GAACD4SMN1; SMN2KDM4E | |
| Ammonia Solution, Strong SCHEMBL4753298 | 0.77 | CA1 (0.43) | ALDH1A1PPARGPPARDPPARACD4 | |
| SCHEMBL4753834 | 0.75 | KCNA1 (0.51) | ALDH1A1HTTHPGDSMN1; SMN2KDM4E | |
| SCHEMBL13983989 | 0.73 | KCNA1 (0.66) | ALDH1A1GAAHPGDSMN1; SMN2KDM4E | |
| SCHEMBL4752355 | 0.73 | KCNA1 (0.49) | ALDH1A1HPGDKDM4ELMNA | |
| SCHEMBL10224252 | 0.72 | HDAC6 (0.47) | AKR1C3CD4HPGDSMN1; SMN2MAPT | |
| SCHEMBL4753862 | 0.72 | KCNA1 (0.65) | ALDH1A1HTTHPGDSMN1; SMN2KDM4E | |
| SCHEMBL4753275 | 0.72 | KCNA1 (0.53) | ALDH1A1GAAHTTHPGDSMN1; SMN2 | |
| SCHEMBL13983878 | 0.71 | CD4 (0.51) | ALDH1A1CD4POLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008149163-A2 | POTASSIUM ION CHANNEL MODULATORS AND USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2008-12-11 | — | — | WO | disclosed |