Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | CD4 | P01730 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL4811566 | 0.79 | KDM4E (0.51) | CA1CA2CA9MAPTKDM4E | |
| SCHEMBL4751184 | 0.78 | KDM4E (0.52) | CA1CA2CA9MAPTKDM4E | |
| SCHEMBL4753300 | 0.77 | ALDH1A1 (0.45) | MAPTKDM4EHTTSMN1; SMN2LMNA | |
| SCHEMBL10224252 | 0.73 | HDAC6 (0.47) | MAPTSMN1; SMN2LMNAOPRM1OPRK1 | |
| SCHEMBL13983878 | 0.72 | CD4 (0.51) | HTTALDH1A1CD4 | |
| SCHEMBL3532188 | 0.66 | KDR (0.49) | MAPTKDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL13302259 | 0.66 | KMT2A (0.77) | MAPTKDM4EKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL4753834 | 0.65 | KCNA1 (0.51) | MAPTKDM4EL3MBTL1KMT2AMEN1 | |
| SCHEMBL13983989 | 0.64 | KCNA1 (0.66) | MAPTKDM4ESMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL976355 | 0.64 | F10 (0.45) | MAPTKMT2ASMN1; SMN2LMNAPAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008149163-A2 | POTASSIUM ION CHANNEL MODULATORS AND USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2008-12-11 | — | — | WO | disclosed |