Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13985524 | 1.00 | MEN1 (0.40) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL13985516 | 0.83 | USP14 (0.38) | POLB | |
| SCHEMBL4755761 | 0.81 | SLC6A3 (0.39) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL4755656 | 0.81 | MEN1 (0.39) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL4755659 | 0.81 | MEN1 (0.39) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL4790013 | 0.80 | MCHR1 (0.35) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL13985505 | 0.80 | MCHR1 (0.35) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL4756481 | 0.74 | CRHR1 (0.41) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL4753362 | 0.74 | SMN1; SMN2 (0.40) | MEN1KMT2AALDH1A1KDM4ENPC1 | |
| SCHEMBL13985522 | 0.74 | CRHR1 (0.41) | MEN1KMT2AALDH1A1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | claimed |
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |