Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 4/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
| ▸ | PDE1A | P54750 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755765 | 0.88 | CHRNB2 (0.34) | SPRAVPR1A | |
| SCHEMBL4755767 | 0.88 | CHRNB2 (0.34) | SPRAVPR1A | |
| SCHEMBL4789984 | 0.86 | KCNH2 (0.32) | SPRPDE1APDE1BPDE1C | |
| SCHEMBL4755166 | 0.85 | AVPR1A (0.39) | AVPR1A | |
| SCHEMBL4755169 | 0.85 | AVPR1A (0.39) | AVPR1A | |
| SCHEMBL4753244 | 0.83 | DRD2 (0.41) | AVPR1A | |
| SCHEMBL4753245 | 0.83 | DRD2 (0.41) | AVPR1A | |
| SCHEMBL4755213 | 0.82 | DRD1 (0.40) | — | |
| SCHEMBL4755215 | 0.82 | DRD1 (0.40) | — | |
| SCHEMBL4755594 | 0.82 | DRD1 (0.37) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | claimed |
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | disclosed |