Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 15/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3038994 | 0.88 | LTA4H (0.57) | LTA4HSIGMAR1KMT2AALDH1A1 | |
| SCHEMBL4753500 | 0.88 | LTA4H (0.44) | LTA4HSIGMAR1KMT2AALDH1A1 | |
| SCHEMBL4757643 | 0.86 | LTA4H (0.42) | LTA4HSIGMAR1KMT2AALDH1A1 | |
| SCHEMBL4757698 | 0.84 | LTA4H (0.52) | LTA4HALDH1A1 | |
| SCHEMBL3036713 | 0.81 | LTA4H (0.56) | LTA4HALDH1A1 | |
| SCHEMBL4755387 | 0.81 | LTA4H (0.53) | LTA4HSIGMAR1ALDH1A1 | |
| SCHEMBL3037103 | 0.80 | LTA4H (0.65) | LTA4H | |
| SCHEMBL3036296 | 0.80 | LTA4H (0.56) | LTA4H | |
| SCHEMBL4757592 | 0.80 | LTA4H (0.38) | LTA4HSIGMAR1KMT2A | |
| SCHEMBL27810028 | 0.79 | KMT2A (0.56) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1976828-A1 | DIAMINE DERIVATIVES AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE | Schering Aktiengesellschaft (DE) | 2008-10-08 | — | — | EP | claimed |
| WO-2007079078-A1 | DIAMINE DERIVATIVES AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2007-07-12 | — | — | WO | claimed |