Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753309 | 0.93 | NPC1 (0.37) | FFAR4NPC1DHFRALDH1A1LMNA | |
| SCHEMBL28978441 | 0.86 | DHFR (0.40) | NPC1DHFRALDH1A1LMNAKMT2A | |
| SCHEMBL28493074 | 0.84 | DHFR (0.40) | NPC1DHFRALDH1A1LMNAKMT2A | |
| SCHEMBL4753358 | 0.84 | POLB (0.42) | FFAR4NPC1DHFRALDH1A1HTR2A | |
| SCHEMBL4750889 | 0.83 | POLB (0.42) | NPC1DHFRALDH1A1LMNAKMT2A | |
| SCHEMBL4751039 | 0.80 | ALDH1A1 (0.45) | FFAR4NPC1ALDH1A1LMNAKMT2A | |
| SCHEMBL28496894 | 0.78 | KMT2A (0.39) | NPC1DHFRALDH1A1LMNAKMT2A | |
| SCHEMBL30110206 | 0.76 | MAOB (0.44) | NPC1ALDH1A1KMT2AMAPT | |
| SCHEMBL4049990 | 0.75 | LMNA (0.45) | NPC1ALDH1A1LMNAKMT2APOLB | |
| SCHEMBL3183533 | 0.74 | NPC1 (0.56) | NPC1ALDH1A1LMNAKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146063-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT6 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR Nyilvánosan Müködö Részvénytársagág (HU) | 2008-12-04 | — | — | WO | disclosed |