Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 2/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CDC7 | O00311 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4750889 | 0.94 | POLB (0.42) | POLBMAPTDHFRHTR2ANPC1 | |
| SCHEMBL4754289 | 0.84 | FFAR4 (0.39) | POLBMAPTDHFRHTR2ANPC1 | |
| SCHEMBL28978441 | 0.84 | DHFR (0.40) | POLBMAPTDHFRHTR2ANPC1 | |
| SCHEMBL4753309 | 0.83 | NPC1 (0.37) | POLBMAPTDHFRHTR2ANPC1 | |
| SCHEMBL28493074 | 0.82 | DHFR (0.40) | POLBMAPTDHFRHTR2ANPC1 | |
| SCHEMBL4753173 | 0.81 | MAPT (0.41) | POLBMAPTNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28496894 | 0.76 | KMT2A (0.39) | MAPTDHFRHTR2ANPC1ALDH1A1 | |
| SCHEMBL30110206 | 0.74 | MAOB (0.44) | MAPTNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4750822 | 0.74 | CHRNB2 (0.44) | POLBMAPTNPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4049990 | 0.70 | LMNA (0.45) | POLBMAPTNPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008146063-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT6 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR Nyilvánosan Müködö Részvénytársagág (HU) | 2008-12-04 | — | — | WO | disclosed |