Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 3/20 | 0.39 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | SMO | Q99835 | 1/20 | 0.38 |
| ▸ | KAT7 | O95251 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4757789 | 0.81 | KAT6A (0.42) | KAT6AKAT5MAPK14SMOKAT7 | |
| SCHEMBL4755015 | 0.77 | KAT6A (0.39) | KAT6AKAT5MAPK14SMOKAT7 | |
| SCHEMBL4758284 | 0.75 | SMN1; SMN2 (0.47) | SMN1; SMN2MEN1KMT2AHPGDGAA | |
| SCHEMBL13985036 | 0.72 | SMN1; SMN2 (0.53) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL4757779 | 0.72 | HDAC3 (0.44) | SMN1; SMN2MEN1KMT2ALMNAMAPK1 | |
| SCHEMBL4755128 | 0.69 | MAPK14 (0.44) | MAPK14SMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL23519742 | 0.67 | SMN1; SMN2 (0.46) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL4758264 | 0.67 | WDR91 (0.40) | SMN1; SMN2MEN1KMT2AHPGDKDM4E | |
| SCHEMBL27158903 | 0.63 | L3MBTL1 (0.67) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL2638020 | 0.63 | MEN1 (0.59) | SMN1; SMN2MEN1KMT2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009000819-A1 | 5-PHENYL-1,3,4-OXADIAZOL-2-YL-ACETYL-4-PIPERIDINYL DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |
| WO-2009000819-A1 | 5-PHENYL-1,3,4-OXADIAZOL-2-YL-ACETYL-4-PIPERIDINYL DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |