Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KAT5 | Q92993 | 2/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | SMO | Q99835 | 1/20 | 0.38 |
| ▸ | KAT7 | O95251 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4757789 | 0.83 | KAT6A (0.42) | KAT6AALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL4755065 | 0.77 | KAT6A (0.39) | KAT6AALDH1A1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL4756995 | 0.74 | DYRK1A (0.47) | ALDH1A1MAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL26077234 | 0.73 | KMT2A (0.46) | ALDH1A1KDM4EMAPTSMN1; SMN2KMT2A | |
| SCHEMBL8440378 | 0.71 | ALDH1A1 (0.60) | ALDH1A1KDM4EMAPTSMN1; SMN2KMT2A | |
| SCHEMBL588343 | 0.71 | ALDH1A1 (0.62) | ALDH1A1KDM4EMAPTSMN1; SMN2KMT2A | |
| SCHEMBL67540 | 0.71 | ALDH1A1 (0.62) | ALDH1A1KDM4EMAPTSMN1; SMN2KMT2A | |
| SCHEMBL25262781 | 0.70 | ATAD2 (0.46) | ALDH1A1KDM4EMAPTSMN1; SMN2KMT2A | |
| SCHEMBL4756971 | 0.70 | ALDH1A1 (0.41) | ALDH1A1KDM4EMAPTSMN1; SMN2KMT2A | |
| SCHEMBL4542026 | 0.70 | AXL (0.51) | KAT6AALDH1A1KDM4EMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009000819-A1 | 5-PHENYL-1,3,4-OXADIAZOL-2-YL-ACETYL-4-PIPERIDINYL DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |
| WO-2009000819-A1 | 5-PHENYL-1,3,4-OXADIAZOL-2-YL-ACETYL-4-PIPERIDINYL DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |