Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 4/20 | 0.42 |
| ▸ | KAT5 | Q92993 | 3/20 | 0.41 |
| ▸ | KAT7 | O95251 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | GAA | P10253 | 7/20 | 0.38 |
| ▸ | POLB | P06746 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.34 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755015 | 0.83 | KAT6A (0.39) | KAT6AKAT5KAT7MAPK14SMO | |
| SCHEMBL4755065 | 0.81 | KAT6A (0.39) | KAT6AKAT5KAT7MAPK14SMO | |
| SCHEMBL4756960 | 0.74 | DYRK1A (0.48) | KAT5KAT7KDM4EALDH1A1GAA | |
| SCHEMBL21638091 | 0.70 | KDM4E (0.61) | KDM4EALDH1A1GAAPOLBLMNA | |
| SCHEMBL2635338 | 0.70 | KDM4E (0.61) | KDM4EALDH1A1GAAPOLBLMNA | |
| SCHEMBL4757912 | 0.69 | RXRA (0.38) | KAT6AKAT5KAT7MAPTL3MBTL1 | |
| SCHEMBL4756909 | 0.69 | RXRA (0.37) | KAT6AKAT5KAT7SMN1; SMN2 | |
| SCHEMBL15262407 | 0.68 | KAT6A (0.37) | KAT6AKAT5KAT7MAPK14SMO | |
| SCHEMBL28500403 | 0.68 | P2RX7 (0.47) | KDM4EALDH1A1GAAPOLBMAPT | |
| SCHEMBL3440306 | 0.67 | PLK1 (0.49) | MAPK14SMOKDM4EMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009000819-A1 | 5-PHENYL-1,3,4-OXADIAZOL-2-YL-ACETYL-4-PIPERIDINYL DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |
| WO-2009000819-A1 | 5-PHENYL-1,3,4-OXADIAZOL-2-YL-ACETYL-4-PIPERIDINYL DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |