Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | DRD5 | P21918 | 2/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4753244 | 1.00 | DRD2 (0.41) | DRD2DRD3KCNH2DRD1DRD5 | |
| SCHEMBL4755166 | 0.89 | AVPR1A (0.39) | KCNH2DRD1DRD5AVPR1AKMT2A | |
| SCHEMBL4755169 | 0.89 | AVPR1A (0.39) | KCNH2DRD1DRD5AVPR1AKMT2A | |
| SCHEMBL4755213 | 0.89 | DRD1 (0.40) | DRD1DRD5NR1H2NR1H3KMT2A | |
| SCHEMBL4755215 | 0.89 | DRD1 (0.40) | DRD1DRD5NR1H2NR1H3KMT2A | |
| SCHEMBL4755829 | 0.85 | PHGDH (0.33) | DRD2DRD3KCNH2AVPR1ANR1H2 | |
| SCHEMBL4755836 | 0.85 | PHGDH (0.33) | DRD2DRD3KCNH2AVPR1ANR1H2 | |
| SCHEMBL4755594 | 0.84 | DRD1 (0.37) | DRD1DRD5GRM5KMT2ACYP1A2 | |
| SCHEMBL4755592 | 0.84 | DRD1 (0.37) | DRD1DRD5GRM5KMT2ACYP1A2 | |
| SCHEMBL4755651 | 0.83 | SPR (0.32) | AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008156607-A1 | SUBSTITUTED PYRIMIDINONES | NEUROGEN CORPORATION (US) | 2008-12-24 | — | — | WO | claimed |