Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALCRL | Q16602 | 8/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4756936 | 0.88 | CALCRL (0.53) | CALCRLGAAMAPTSMN1; SMN2DGAT1 | |
| SCHEMBL4758257 | 0.82 | RXRA (0.43) | CALCRLMAPTSMN1; SMN2MEN1USP2 | |
| SCHEMBL13985180 | 0.76 | SMN1; SMN2 (0.53) | CALCRLGAAMAPTSMN1; SMN2POLB | |
| SCHEMBL4758251 | 0.76 | CALCRL (0.46) | CALCRLMAPTSMN1; SMN2MEN1USP2 | |
| SCHEMBL4757912 | 0.75 | RXRA (0.38) | CALCRLMAPTSMN1; SMN2 | |
| SCHEMBL4757784 | 0.75 | CALCRL (0.53) | CALCRLMAPTSMN1; SMN2 | |
| SCHEMBL4755690 | 0.74 | CALCRL (0.40) | CALCRLMAPTSMN1; SMN2 | |
| SCHEMBL4756909 | 0.74 | RXRA (0.37) | CALCRLSMN1; SMN2 | |
| SCHEMBL4757909 | 0.74 | CALCRL (0.73) | CALCRL | |
| SCHEMBL4755125 | 0.73 | TP53 (0.45) | CALCRLMAPTSMN1; SMN2DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009000819-A1 | 5-PHENYL-1,3,4-OXADIAZOL-2-YL-ACETYL-4-PIPERIDINYL DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |
| WO-2009000819-A1 | 5-PHENYL-1,3,4-OXADIAZOL-2-YL-ACETYL-4-PIPERIDINYL DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |