Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 3/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 2/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1813007 | 0.98 | MAPT (0.38) | MAPTGAAKDM4EKDM1ACNR2 | |
| SCHEMBL9500423 | 0.81 | ALDH1A1 (0.38) | MAPTGAAKDM4EKDM1ACNR2 | |
| Hydrochloric Acid SCHEMBL3633973 | 0.80 | ALDH1A1 (0.37) | MAPTGAAKDM4EKDM1ACNR2 | |
| SCHEMBL5338489 | 0.77 | ALDH1A1 (0.34) | MAPTKDM4EALDH1A1POLBRAB9A | |
| SCHEMBL3360974 | 0.75 | MAPT (0.42) | MAPTKDM4EKDM1ANCF1ALDH1A1 | |
| SCHEMBL28661274 | 0.75 | MAPT (0.52) | MAPTGAAKDM4EKDM1ACNR2 | |
| SCHEMBL13386271 | 0.74 | RAB9A (0.38) | MAPTGAAKDM4EALDH1A1POLB | |
| SCHEMBL13386109 | 0.74 | CA2 (0.35) | MAPTGAAALDH1A1NQO2TDP1 | |
| SCHEMBL50667 | 0.73 | MAPT (0.56) | MAPTGAAKDM4EALDH1A1POLB | |
| Iodide SCHEMBL2593593 | 0.73 | NQO2 (0.36) | MAPTGAAKDM4EALDH1A1NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116687936-A | New application of phenothiazines or compounds with similar structures in pharmacy | 广州威溶特医药科技有限公司 | 2023-09-05 | — | — | CN | claimed |
| CN-112426521-B | New application of phenothiazines or compounds with similar structures in pharmacy | 广州威溶特医药科技有限公司 | 2023-08-01 | — | — | CN | claimed |
| CN-112426521-A | New application of phenothiazines or compounds with similar structures in pharmacy | 广州威溶特医药科技有限公司 | 2021-03-02 | — | — | CN | claimed |
| US-20240228949-A1 | METHOD AND COMPOSITION FOR REPROGRAMMING CELLS | CHALIFOUX, Joseph (US) | 2024-07-11 | — | — | US | disclosed |
| CN-116687936-A | New application of phenothiazines or compounds with similar structures in pharmacy | 广州威溶特医药科技有限公司 | 2023-09-05 | — | — | CN | disclosed |
| CN-112426521-B | New application of phenothiazines or compounds with similar structures in pharmacy | 广州威溶特医药科技有限公司 | 2023-08-01 | — | — | CN | disclosed |
| CN-116410155-A | Method for preparing 3, 7-bis (dimethylamino) phenothiazin-5-ium iodide | 普如制药生命解决方案公司 | 2023-07-11 | — | — | CN | disclosed |
| CN-116133650-A | Methylene blue and riboflavin for prophylactic and therapeutic antiviral therapies | E·H·塞尔尼 | 2023-05-16 | — | — | CN | disclosed |
| CN-110382472-B | Method for preparing 3, 7-bis (dimethylamino) phenothiazin-5-ium iodide | 普如制药生命解决方案公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-112426521-A | New application of phenothiazines or compounds with similar structures in pharmacy | 广州威溶特医药科技有限公司 | 2021-03-02 | — | — | CN | disclosed |
| WO-2008155691-A1 | NON-WOVEN WEBS MADE FROM TREATED FIBRES | THE PROCTER & GAMBLE COMPANY (US) | 2008-12-24 | — | — | WO | disclosed |
| WO-2007144048-A2 | PRESENTATION FORM FOR THE ORAL ADMINISTRATION OF PHENOTHIAZINE DYES, ITS PRODUCTION AND USE | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO. KG (AT) | 2007-12-21 | — | — | WO | disclosed |