Hydrochloric Acid

Hydrochloric Acid

SCHEMBL3633973

CN(C)c1ccc2[s+]c3ccccc3nc2c1N(C)C.[Cl-]

nearest known ligand 0.37

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.37
KDM4E B2RXH2 1/20 0.37
POLB P06746 1/20 0.37
GAA P10253 1/20 0.37
MEN1 O00255 1/20 0.35
HCRTR1 O43613 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
THRB P10828 1/20 0.35
MAPK1 P28482 1/20 0.35
RAB9A P51151 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
KDM1A O60341 2/20 0.32
NCF1 P14598 1/20 0.32
EP300 Q09472 1/20 0.31
KAT2B Q92831 1/20 0.31
KAT8 Q9H7Z6 1/20 0.31
CNR2 P34972 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9500423 0.98 ALDH1A1 (0.38) ALDH1A1KDM4EPOLBGAAMEN1
Hydrochloric Acid SCHEMBL1813007 0.82 MAPT (0.38) ALDH1A1KDM4EPOLBGAAMEN1
SCHEMBL4756517 0.80 MAPT (0.39) ALDH1A1KDM4EPOLBGAAMEN1
Hydrochloric Acid SCHEMBL31542018 0.71 MAPT (0.53) ALDH1A1KDM4EPOLBGAAMEN1
Hydrochloric Acid SCHEMBL740017 0.71 MAPT (0.53) ALDH1A1KDM4EPOLBGAAMEN1
SCHEMBL13386155 0.70 KDM1A (0.36) ALDH1A1KDM4EPOLBMEN1HCRTR1
SCHEMBL3360974 0.70 MAPT (0.42) ALDH1A1KDM4EPOLBMEN1LMNA
SCHEMBL11590632 0.69 MAPT (0.41) ALDH1A1KDM4EPOLBGAAMEN1
Water SCHEMBL1146714 0.69 MAPT (0.50) ALDH1A1KDM4EPOLBGAAMEN1
SCHEMBL50667 0.69 MAPT (0.56) ALDH1A1KDM4EPOLBGAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3790491-A1 SYSTEMS FOR AUGMENTED REALITY SURGICAL AND CLINICAL VISUALIZATION Memorial Sloan Kettering Cancer Center (US) 2021-03-17 EP disclosed
EP-3787684-A1 NANOTHERAPEUTIC SYSTEMS AND METHODS USING PARTICLE-DRIVEN PHOTODYNAMIC THERAPY (PDT) Memorial Sloan Kettering Cancer Center (US) 2021-03-10 EP disclosed
WO-2019217893-A1 SYSTEMS FOR AUGMENTED REALITY SURGICAL AND CLINICAL VISUALIZATION MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2019-11-14 WO disclosed
EP-2190402-A1 BIOTIN AND SILICA TO COUNTER AGEING OF HAIR Henkel AG & Co. KGaA (DE) 2010-06-02 EP disclosed
EP-2167030-A2 AGENTS COMPRISING AN ANTI-IRRITANT ACTIVE SUBSTANCE Henkel AG & Co. KGaA (DE) 2010-03-31 EP disclosed
WO-2009155115-A2 COATINGS AND SURFACE TREATMENTS HAVING ACTIVE ENZYMES AND PEPTIDES REACTIVE SURFACES, LTD. (US) 2009-12-23 WO disclosed
WO-2009040149-A1 BIOTIN AND SILICA TO COUNTER AGEING OF HAIR HENKEL AG & CO. KGAA (DE) 2009-04-02 WO disclosed
WO-2009010415-A2 AGENTS COMPRISING AN ANTI-IRRITANT ACTIVE SUBSTANCE HENKEL AG & CO. KGAA (DE) 2009-01-22 WO disclosed
WO-2001009055-A9 METHOD FOR PRETREATING COMPONENTS OF A CEMENTITIOUS COMPOSITION TO CONTROL ADSORPTION POTENTIAL YOUNG ROBERT DOUGLAS (US) 2002-09-12 WO disclosed
EP-1051249-A1 FLOW DEVICES FOR THE REDUCTION OF COMPOUNDS FROM BIOLOGICAL COMPOSITIONS AND METHODS OF USE Cerus Corporation (US) 2000-11-15 EP disclosed
WO-1999034915-A1 FLOW DEVICES FOR THE REDUCTION OF COMPOUNDS FROM BIOLOGICAL COMPOSITIONS AND METHODS OF USE CERUS CORPORATION (US) 1999-07-15 WO disclosed
US-5909114-A Coulometric analysis method and a device therefor NAKANO VINEGAR CO., LTD. (JP) 1999-06-01 US disclosed
US-5726565-A FOR QUANTITATIVE DETERMINATION OF A SAMPLE SUBSTANCE NAKANO VINEGAR CO., LTD. (JP) 1998-03-10 US disclosed