Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4756971 | 0.82 | ALDH1A1 (0.41) | GRM5ALDH1A1TSHRMEN1MAPT | |
| SCHEMBL4757757 | 0.79 | GPR119 (0.43) | GRM5ALDH1A1TSHRCYP2C19NPSR1 | |
| SCHEMBL4757752 | 0.78 | TPMT (0.47) | GRM5ALDH1A1TSHRNPSR1MEN1 | |
| SCHEMBL5869072 | 0.70 | ALOX15 (0.55) | ALDH1A1MEN1KMT2AGABRA2GABRB2 | |
| SCHEMBL6580266 | 0.69 | ALDH1A1 (0.59) | GPR35PLA2G1BATG4BJMJD6ALDH1A1 | |
| SCHEMBL6057293 | 0.67 | CHRM2 (0.55) | GPR35JMJD6ALDH1A1TSHRCYP2C19 | |
| SCHEMBL6057138 | 0.65 | ALDH1A1 (0.55) | GPR35PLA2G1BATG4BALDH1A1TSHR | |
| SCHEMBL9639553 | 0.65 | ALDH1A1 (0.50) | GPR35PLA2G1BATG4BJMJD6ALDH1A1 | |
| SCHEMBL559800 | 0.65 | GPR35 (0.53) | GPR35PLA2G1BATG4BJMJD6ALDH1A1 | |
| SCHEMBL20068189 | 0.64 | ESR1 (0.58) | GPR35PLA2G1BATG4BJMJD6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009000819-A1 | 5-PHENYL-1,3,4-OXADIAZOL-2-YL-ACETYL-4-PIPERIDINYL DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |