Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4757757 | 0.85 | GPR119 (0.43) | ALDH1A1MEN1KMT2AMAPTLMNA | |
| SCHEMBL4757752 | 0.84 | TPMT (0.47) | ALDH1A1MEN1KMT2ASMN1; SMN2TSHR | |
| SCHEMBL4756946 | 0.82 | GPR35 (0.42) | ALDH1A1MEN1KMT2AMAPTTSHR | |
| SCHEMBL588343 | 0.73 | ALDH1A1 (0.62) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL67540 | 0.73 | ALDH1A1 (0.62) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL4755015 | 0.70 | KAT6A (0.39) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL30661671 | 0.70 | KDM4E (0.46) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL30570165 | 0.70 | CNR2 (0.56) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL8979351 | 0.70 | CNR2 (0.56) | ALDH1A1KDM4EMEN1KMT2AMAPT | |
| SCHEMBL7827674 | 0.70 | ALDH1A1 (0.45) | ALDH1A1KDM4EMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009000819-A1 | 5-PHENYL-1,3,4-OXADIAZOL-2-YL-ACETYL-4-PIPERIDINYL DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |
| WO-2009000819-A1 | 5-PHENYL-1,3,4-OXADIAZOL-2-YL-ACETYL-4-PIPERIDINYL DERIVATIVES AS CGRP RECEPTOR ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2008-12-31 | — | — | WO | disclosed |