Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.32 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5533178 | 0.81 | HCAR2 (0.39) | TSHRMAPK1NOTUMPDK1PDK2 | |
| SCHEMBL4755368 | 0.80 | HCAR2 (0.36) | NOTUMHDAC4 | |
| SCHEMBL4757278 | 0.77 | CYP2C9 (0.34) | TSHRMEN1KMT2ANOTUMCYP2C9 | |
| SCHEMBL4826843 | 0.73 | HCAR3 (0.39) | TSHRMEN1KMT2AMAPK1LMNA | |
| SCHEMBL4814956 | 0.71 | ALDH1A1 (0.32) | KMT2AALDH1A1 | |
| SCHEMBL8511172 | 0.70 | CYP2C9 (0.45) | TSHRMEN1KMT2ANOTUMCYP2C9 | |
| SCHEMBL9101372 | 0.68 | TSHR (0.37) | TSHRMEN1KMT2ANOTUMCYP2C9 | |
| SCHEMBL2365028 | 0.68 | TSHR (0.37) | TSHRMEN1KMT2ANOTUMCYP2C9 | |
| SCHEMBL4758577 | 0.68 | TSHR (0.36) | TSHRMEN1KMT2ANOTUMCYP2C9 | |
| SCHEMBL7418565 | 0.64 | CYP2C9 (0.33) | TSHRMEN1KMT2ANOTUMCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008006070-A2 | COMPOUNDS AND COMBINATIONS THEREOF FOR INHIBITING BETA-AMYLOID PRODUCTION AND METHODS OF USE THEREOF | ROSKAMP RESEARCH LLC (US) | 2008-01-10 | — | — | WO | disclosed |