SCHEMBL4757728

SCHEMBL4757728

O=Cc1ccc(O)c(C(=O)NCCO)c1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.55
KDM4E B2RXH2 3/20 0.55
MAPT P10636 1/20 0.55
CASP1 P29466 1/20 0.55
CASP7 P55210 1/20 0.55
CDK1 P06493 1/20 0.52
PTGS2 P35354 1/20 0.46
RAB9A P51151 1/20 0.46
NAAA Q02083 1/20 0.44
CA12 O43570 2/20 0.41
CA1 P00915 2/20 0.41
CA2 P00918 2/20 0.41
CA3 P07451 2/20 0.41
CA4 P22748 2/20 0.41
CA6 P23280 2/20 0.41
CA5A P35218 2/20 0.41
CA7 P43166 2/20 0.41
CA9 Q16790 2/20 0.41
CA13 Q8N1Q1 2/20 0.41
CA14 Q9ULX7 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4756900 0.84 HPGD (0.47) ALDH1A1MAPTCDK1PTGS2NAAA
SCHEMBL7200199 0.82 NAAA (0.68) ALDH1A1KDM4ECDK1PTGS2NAAA
SCHEMBL14028746 0.81 NAAA (0.56) ALDH1A1KDM4ECDK1PTGS2NAAA
Gentisic Acid Ethanolamide SCHEMBL1179368 0.80 NAAA (0.65) ALDH1A1KDM4EMAPTCASP1CASP7
Gentisic Acid Ethanolamide SCHEMBL29379843 0.80 NAAA (0.65) ALDH1A1KDM4EMAPTCASP1CASP7
SCHEMBL16864511 0.79 MAOA (0.51) ALDH1A1KDM4EPTGS2RAB9ANAAA
SCHEMBL15776357 0.79 ALDH1A1 (0.42) ALDH1A1KDM4EMAPTCASP1CASP7
SCHEMBL16864512 0.78 CDK1 (0.44) ALDH1A1KDM4EMAPTCDK1PTGS2
SCHEMBL30107654 0.78 ACHE (0.47) ALDH1A1KDM4ENAAACA12CA1
SCHEMBL13313915 0.78 ACHE (0.47) ALDH1A1KDM4ENAAACA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1879661-A1 AGENT FOR DYEING KERATIN-BASED FIBRES HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2008-01-23 EP claimed
WO-2006119821-A1 AGENT FOR DYEING KERATIN-BASED FIBRES HENKEL KOMMANDITGESELLCHAFT AUF AKTIEN (DE) 2006-11-16 WO claimed