Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.68 |
| ▸ | EGFR | P00533 | 2/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.54 |
| ▸ | SYK | P43405 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14028746 | 0.88 | NAAA (0.56) | NAAAEGFRALOX5PTGS2SYK | |
| SCHEMBL7193295 | 0.83 | PDE10A (0.49) | NAAAAPPALDH1A1HPGDLMNA | |
| SCHEMBL4757728 | 0.82 | ALDH1A1 (0.55) | NAAAPTGS2HTTCDK1ALDH1A1 | |
| SCHEMBL4756900 | 0.82 | HPGD (0.47) | NAAAPTGS2HTTCDK1ALDH1A1 | |
| SCHEMBL9235501 | 0.81 | ACHE (0.50) | NAAASYKCDK1ALDH1A1KDM4E | |
| SCHEMBL9785906 | 0.81 | NAAA (1.00) | NAAAEGFRALOX5PTGS2SYK | |
| SCHEMBL5488260 | 0.81 | NAAA (1.00) | NAAAEGFRALOX5PTGS2SYK | |
| SCHEMBL3626446 | 0.81 | NAAA (1.00) | NAAAEGFRALOX5PTGS2SYK | |
| SCHEMBL18645728 | 0.81 | NAAA (0.74) | NAAAEGFRALOX5PTGS2SYK | |
| SCHEMBL11212195 | 0.81 | NAAA (1.00) | NAAAEGFRALOX5PTGS2SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313731-A1 | THIAZOLIDINE DERIVATIVES AND ITS USE AS ANTIFUNGAL AGENT | Oxford GlycoSciences (UK) Limited (GB) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002022612-A1 | THIAZOLIDINE DERIVATIVES AND ITS USE AS ANTIFUNGAL AGENT | OXFORD GLYCOSCIENCES (UK) LIMITED (GB) | 2002-03-21 | — | — | WO | disclosed |