Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 11/20 | 0.40 |
| ▸ | ITGAV | P06756 | 3/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4757913 | 0.87 | GAA (0.41) | GAAITGB3ITGAVITGA2BF2R | |
| SCHEMBL4757908 | 0.79 | ITGB3 (0.42) | GAAITGB3ITGAVITGA2BF2R | |
| SCHEMBL687571 | 0.76 | ALDH1A1 (0.50) | ITGB3ITGAVITGA2BLMNA | |
| SCHEMBL686731 | 0.75 | MAPT (0.55) | LMNA | |
| SCHEMBL687749 | 0.75 | GAA (0.48) | GAAITGB3ITGAVITGA2BCASP1 | |
| SCHEMBL687253 | 0.74 | ITGB3 (0.44) | ITGB3ITGAVITGA2BF2R | |
| SCHEMBL688325 | 0.74 | ALDH1A1 (0.51) | ITGB3ITGAVITGA2BLMNA | |
| SCHEMBL695420 | 0.74 | MAPT (0.54) | ITGB3ITGA2BLMNA | |
| SCHEMBL4428450 | 0.74 | POLB (0.41) | GAAITGB3ITGAVITGA2BCASP1 | |
| SCHEMBL686838 | 0.74 | PTGER3 (0.51) | ITGB3ITGAVITGA2BCASP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1176956-B1 | CARBOXYLIC ACID DERIVATIVES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | ENCYSIVE PHARMACEUTICALS INC (US) | 2008-01-09 | — | — | EP | disclosed |