Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 14/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.40 |
| ▸ | ITGAV | P06756 | 6/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | F2R | P25116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4757905 | 0.87 | GAA (0.40) | GAAITGB3ITGA2BITGAVTAS1R3 | |
| SCHEMBL4757908 | 0.83 | ITGB3 (0.42) | GAAITGB3ITGA2BITGAVF2R | |
| SCHEMBL687571 | 0.81 | ALDH1A1 (0.50) | ITGB3ITGA2BITGAV | |
| SCHEMBL686731 | 0.80 | MAPT (0.55) | — | |
| SCHEMBL687749 | 0.79 | GAA (0.48) | GAAITGB3ITGA2BITGAV | |
| SCHEMBL687253 | 0.79 | ITGB3 (0.44) | ITGB3ITGA2BITGAVF2R | |
| SCHEMBL695420 | 0.79 | MAPT (0.54) | ITGB3ITGA2B | |
| SCHEMBL688325 | 0.79 | ALDH1A1 (0.51) | ITGB3ITGA2BITGAV | |
| SCHEMBL686838 | 0.78 | PTGER3 (0.51) | ITGB3ITGA2BITGAV | |
| SCHEMBL687812 | 0.78 | POLB (0.45) | ITGB3ITGA2BITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1176956-B1 | CARBOXYLIC ACID DERIVATIVES THAT INHIBIT THE BINDING OF INTEGRINS TO THEIR RECEPTORS | ENCYSIVE PHARMACEUTICALS INC (US) | 2008-01-09 | — | — | EP | disclosed |